Missouri Tickborne Disease Story Map

Missouri Department of Health and Senior Services – Bureau of Communicable Disease Control and Prevention, Zoonotic Disease Program

Developed in Collaboration with: Missouri Environmental Public Health Tracking Program and the Information Technology Services Division's Office of Geospatial Information with funding through Missouri Environmental Health Capacity Grant

Image courtesy of the Missouri Department of Conservation

About Tickborne Diseases

Between 1900 to 2020, 18 different tickborne diseases were discovered to cause human illness. More than half of these diseases were identified within the last 40 years. Human case numbers per year for all tickborne diseases are generally on the rise.

This upward trend is partially due to better recognition and disease reporting. It is also a reflection of changes in the environment that foster increased exposure and transmission to humans.

Lifecycle

In Missouri, most of the ticks that pose a public health risk are known as three-host ticks.

This means that they will feed on three hosts during their lifetime. This is an example of what their life cycle looks like.

Ticks must find a host and ingest a blood meal before they can molt and mature to the next stage in their life cycle. 

Ticks become infected with a disease-causing agent by feeding on infected animals.

A tick can pick up a disease-causing agent from a rabbit or other animal. Later in its life cycle, it can then transmit that disease to a human, domestic pets, or wildlife.

Many tickborne diseases have been reported in Missouri residents: Rocky Mountain spotted fever (RMSF), ehrlichiosis, tularemia, Lyme disease, Heartland virus, and Bourbon virus. 

The most commonly reported tickborne diseases in Missouri are ehrlichiosis and Rocky Mountain spotted fever (RMSF).

Signs and Symptoms

The signs and symptoms of tickborne disease vary among individuals and differ according to the infecting agent.

Common symptoms include fever, headache, muscle or joint aches, nausea, vomiting or diarrhea.

If these symptoms occur following a tick bite, or even after exposure to a tick habitat, talk with your health care provider right away.

Prevention

Tick exposure can occur year-round, but ticks are most active during warmer months (April-September). To protect yourself and your family from tick bites, try the following tips:

Know where to expect ticks:

Ticks live in grassy, brushy, or wooded areas, or even on animals. Spending time outside walking your dog, camping, gardening, or hunting could bring you in close contact with ticks. Many people get ticks in their own yard or neighborhood. 

Reduce contact with ticks by avoiding areas with tall grass and wooded or brushy areas. If hiking, try to walk in the center of trails to reduce contact with vegetation along the trail edge.

Wear light-colored clothing to help you spot ticks more easily while outdoors. Also, tuck or tape your pant legs into your socks to prevent access to skin. When returning indoors, place clothing in the dryer on high heat for several minutes to kill any ticks that might be on the clothing.

If you are likely to have exposure to a tick habitat, then consider treating clothing and gear with products containing permethrin. Permethrin can be used to treat boots, clothing and camping gear and remain protective through several washings. Alternatively, you can buy permethrin-treated clothing and gear.

Apply an  Environmental Protection Agency (EPA)-registered insect repellent  containing DEET, picaridin, IR3535, Oil of Lemon Eucalyptus (OLE), para-menthanediol (PMD), or 2-undecanone to any exposed skin.

Carefully check your body for ticks. Ticks attach on people in many places, but are most frequently found around the head, neck, underarms, and between the legs. Remove any attached ticks immediately.

Don’t forget to check your pets for ticks! Talk with your pet’s veterinarian about tick prevention products.

If you find a tick attached, use clean, fine-tipped tweezers, if possible, to remove the tick. Grasp the tick as close to the skin as possible and pull upward with steady, even pressure until it is removed. Clean the bite site with soap and water or other disinfectant.

Diseases from Common Ticks in Missouri

Ehrlichiosis

Ehrlichiosis is the general name used to describe a group of bacterial diseases caused by Ehrlichia chaffeensisE. ewingii, or E. muris eauclairensis in the United States.

E. chaffeensis and E. ewingii spread to people primarily through the bite of infected Lone Star ticks (Amblyomma americanum).

Lone Star Tick size comparison.

E. muris eauclairensis cases mostly occur in the Upper Midwest. Spread of E. muris eauclairensis occurs through the bite of infected blacklegged ticks (Ixodes scapularis).  

People with ehrlichiosis will often have fever, chills, headache, muscle aches, nausea, vomiting, or diarrhea. Infection is treatable with antibiotics.

Ehrlichiosis caused by E. chaffeensis and E. ewingii is most frequently reported from the southeastern and south-central United States, from the East Coast extending westward to Texas. The majority of reported cases in Missouri are due to infection with E. chaffeensis.

Lone Star Tick (Amblyomma americanum)

Occurrence of Ehrlichiosis in Missouri from 2009 through 2021.

Choose a year to see case rates for each county for that year. Click the button on the top-right of the map to see the legend. Click on a county or jurisdiction to see how many cases were reported there in that year.

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Spotted Fever Rickettsiosis

Rocky Mountain spotted fever (RMSF), the most commonly reported Spotted Fever Rickettsiosis (SFR), is a bacterial disease caused by Rickettsia rickettsii and is spread through the bite of an infected tick.

SFR cases occur throughout the United States, but five states (North Carolina, Tennessee, Missouri, Arkansas, and Oklahoma) account for over 50% of cases.

Most people who get sick with SFR will have a fever, headache, and rash. SFR can be deadly if not treated early with the right antibiotic.  

American Dog Tick (Dermacentor variabilis)

Occurrence of Spotted Fever Rickettsiosis in Missouri from 2009 through 2021.

Choose a year to see case rates for each county for that year. Click the button on the top-right of the map to see the legend. Click on a county or jurisdiction to see how many cases were reported there in that year.

Map Legend

Tularemia

Tularemia is a highly infectious bacterial disease caused by Francisella tularensis. F. tularensis can infect both people and animals. People can become infected in several ways including: tick and deer fly bites, skin contact with infected animals, drinking contaminated water, inhaling contaminated aerosols or agricultural/landscaping dust, or through laboratory exposures. 

Symptoms of infection can vary depending on the route of entry.  Generalized illness can include fever, chills, headache, malaise, fatigue, anorexia, myalgia, chest discomfort, cough, sore throat, vomiting, diarrhea, and abdominal pain. Infection is treatable with antibiotics. 

In Missouri, ticks that transmit F. tularensis bacteria to humans include the dog tick (Dermacentor variabilis) and lone star tick (Amblyomma americanum). The Rocky Mountain wood tick (D. andersoni) can also transmit the bacteria.

Rabbits, hares, and rodents are especially susceptible to tularemia and often die in large numbers during outbreaks. In the United States, naturally occurring infections have been reported from all states except Hawaii. 

Occurrence of tularemia in Missouri from 2009 through 2021.

Choose a year to see case rates for each county for that year. Click the button on the top-right of the map to see the legend. Click on a county or jurisdiction to see how many cases were reported there in that year.

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Lyme Disease

Lyme disease is a bacterial disease caused by Borrelia burgdorferi and rarely, Borrelia mayonii. It is transmitted to humans through the bite of infected blacklegged ticks (I. scapularis). 

Black Legged Tick size comparison.

Typical symptoms include fever, headache, fatigue, and a characteristic skin rash called erythema migrans (EM). If left untreated, infection can spread to joints, the heart, and the nervous system.

The appearance of the EM rash can vary widely.

Lyme disease is diagnosed based on symptoms, physical findings (e.g., rash), and the possibility of exposure to infected ticks. Laboratory testing is helpful if used correctly and performed with validated methods. Most cases of Lyme disease can be treated successfully with a few weeks of antibiotics.

Missouri is considered a low incident state for Lyme disease. Most cases of Lyme disease are reported from the Northeast and Upper Midwest.

Occurrence of Lyme Disease in Missouri from 2009 through 2021.

Choose a year to see case rates for each county for that year. Click the button on the top-right of the map to see the legend. Click on a county or jurisdiction to see how many cases were reported there in that year.

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Anaplasmosis

Anaplasmosis is a bacterial disease caused by Anaplasma phagocytophilum. These bacteria are spread to people by tick bites primarily from the blacklegged tick (Ixodes scapularis) but also the western blacklegged tick (Ixodes pacificus).

Anaplasmosis is most commonly reported in the Northeastern and upper Midwestern states. This infection is not commonly identified in Missouri residents.

People with anaplasmosis will often have fever, headache, chills, and muscle aches. Infection is treatable with antibiotics.

Blacklegged Tick (Ixodes scapularis)

Occurrence of Anaplasmosis in Missouri from 2009 through 2021.

Choose a year to see case rates for each county for that year. Click the button on the top-right of the map to see the legend. Click on a county or jurisdiction to see how many cases were reported there in that year.

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Heartland Virus

Heartland virus belongs to a group of viruses called phleboviruses. Heartland virus is less commonly reported than other tickborne diseases, but cases have been identified in Missouri and other states.  Overall, the virus causes low numbers of infections around the world. The Lone Star tick (Amblyomma americanum) is believed to be a vector of Heartland virus in the United States.

Lone Star Tick female and male.

People infected with Heartland virus will have non-specific signs and symptoms that may include fever, fatigue, decreased appetite, headache, arthralgia, myalgia, nausea, diarrhea and laboratory test results that could include leukopenia, thrombocytopenia, and mild to moderate elevation of liver enzymes.

Many patients infected with Heartland virus have required hospitalization but have fully recovered with supportive care.

Bourbon Virus

Lone Star Tick

Bourbon virus belongs to a group of viruses called Thogotoviruses. Bourbon virus is another uncommonly reported tickborne illness.  It was first discovered in a resident of Bourbon County, Kansas in 2014. The vector for Bourbon virus has not been confirmed, but it is likely to be transmitted by the Lone Star tick (A. americanum) in the United States.

People with Bourbon virus will have non-specific signs and symptoms that may include fever, fatigue, decreased appetite, headache, arthralgia, myalgia, nausea, diarrhea and laboratory test results that could include leukopenia, thrombocytopenia, and mild to moderate elevation of liver enzymes.  

Many patients infected with Bourbon virus have required hospitalization, but have fully recovered with supportive care.


More Information

Lone Star Tick

Lone Star Tick size comparison.

Lone Star Tick (Amblyomma americanum)

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American Dog Tick (Dermacentor variabilis)

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Black Legged Tick size comparison.

The appearance of the EM rash can vary widely.

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Blacklegged Tick (Ixodes scapularis)

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Lone Star Tick female and male.

Story Map Created in Partnership with the  Missouri Office of Geographic Information