Historic Main Street Tour

Much of St. Charles' history can be found in the buildings lining our Main Street which are listed on the National Register of Historic Places. From the site of its first settler Louis Blanchette, to innovators at OPO Startups in the 1909 Post Office, there is a bit of everything! From fur traders and blacksmiths, from Lewis and Clark's Corps and Missouri’s first Statesmen, these are the people that bring these buildings to life and share the history of St. Charles.  As the Missouri River gave way to the Boone's Lick Road and the development of the railroads, we are part of America's westward expansion and the beginning of Missouri's Statehood.  We invite you to explore them here. Each number represents a story of a building and its’ people on St. Charles’ Historic Main Street.